Randomized clinical trial comparing different implant timing protocols following alveolar ridge preservation (ARP)

Randomized clinical trial comparing different implant timing protocols following alveolar ridge preservation (ARP) - ARP/ Early vs Delayed

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

DRKS

Registry ID

DRKS00035032

Enrollment

Registered

2024-10-23

Start date

2025-04-08

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Missing tooth

Interventions

Group 1: SPI® NEVO RC INICELL®, dental implant placement 8 weeks after tooth extraction with alveolar ridge preservation. Group 2: SPI® NEVO RC INICELL®, dental implant placement 6 months after tooth

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: - >18 years of age - Systemically healthy patients - Requiring extraction of at least one upper or lower asymptomatic front tooth or premolar - Presence of at least one neigboring tooth - Bleeding on probing <20% - Plaque index <20% - Capability to comply with the study procedures - Signed Informed Consent Form

Exclusion criteria

Exclusion criteria: - > 80 years of age - Pregnant or lactating women - Skeletal immaturity - Known or suspected non-compliance, drug or alcohol abuse - Smokers (>20 cigarettes/day) - Buccal bony dehiscences up to 50% - Currently taking drugs that influence bone metabolism - History of malignancy, radiotherapy or chemotherapy for malignancy in the past 5 years - Untreated periodontitis - General medical contraindication for implant surgery

Design outcomes

Primary

Measure	Time frame
The primary outcome of this study will be the difficulty of dental implant placement assessed by the clinician.	—

Secondary

Measure	Time frame
Clinical biological outcomes (probing depth (PD), marginal bleeding index (MBI), plaque index (PI), patient’s PICF, and saliva, and radiographic evaluations (marginal bone levels (MBL)), prophilometric measurements, experience of the clinician (years), impant insertion torque and PES will be avaluated at different timepoints.	—

Countries

Switzerland

Contacts

Public ContactStefan Bienz

University of Zurich Center of Dental Medicine Clinic of Reconstructive Dentistry

stefan.bienz@zzm.uzh.ch+41 44 634 04 04

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026