Soft tissue sarcomas, bone sarcomas and gastrointestinal stromal tumors (GIST)
Conditions
Interventions
Group 1: Systematic collection of data on biopsy, surgery and disease progression in patients scheduled for image-guided percutaneous punch biopsy of the space-occupying lesion (soft tissue or bone sa
Sponsors
Radiologische Klinik, Universitätsklinikum Tübingen, Radiologie, Abt. Diagnostische & Interventionelle radiologie
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Patients with suspected soft tissue sarcoma, bone sarcoma or GIST - Indication & performance of an image-guided biopsy of the mass - Indication for neo-adjuvant therapy regimen - Written consent
Exclusion criteria
Exclusion criteria: - Metastatic stage of disease - Patients incapable of giving consent or no written consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assuring and improving the quality of care for sarcoma patients, focusing on biopsies to be performed for primary diagnosis or recurrence. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Rate of biopsies performed according to sarcoma board decision - Biopsy complication rate - Rate of surgery performed after neo-adjuvant therapy according to the sarcoma board decision - Quality of visibility of biopsy channel during surgery - Rate of R0 resections - Rate of concordance of histopathological and molecular pathological features between biopsy and resected tumour specimen - Ability to assess biopsy channel for tumour cell seeding - Rate of patients with tumour progression or recurrence in the area of the biopsy channel (local recurrence) - Progression-free survival (PFS) - Disease-free survival (DFS) - Overall survival (OS) | — |
Countries
Germany
Contacts
Public ContactChristoph K. W. Deinzer
Universitätsklinikum Tübingen, Klinik für Innere Medizin VIII - Medizinische Onkologie & Pneumologie, Zentrums für Weichteilsarkome, GIST & Knochentumoren des CCC Tübingen-Stuttgart
Outcome results
None listed