Gradual reperfusion after cardioplegic cardiac arrest

Gradual reperfusion after cardioplegic cardiac arrest - no acronym

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00034979

Enrollment

Registered

2024-08-30

Start date

2013-02-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardioplegia

Interventions

Group 1: Group A received conventional hyperoxytic reoxygenation, both during cardioplegia administration and after opening of the aortic clamp Group 2: Group B received cardioplegia in the sense of g

Eligibility

Sex/Gender

All

Age

50 Years to No maximum

Inclusion criteria

Inclusion criteria: Heart Surgery Aortic clamping time >90 min.

Exclusion criteria

Exclusion criteria: Surgical procedures that result in a larger myocardial lesion

Design outcomes

Primary

Measure	Time frame
Troponin T as a highly specific marker of even the smallest heart muscle damage. Melondialdehyde in coronary sinus as a marker of ischemia-reperfusion damage Endpoints were measured before EKZ, 15min, 30min, 60min, 2h, 8h, 24h and 48h	—

Secondary

Measure	Time frame
Myeloperoxidase as a marker of ischemia-reperfusion damage. Myocardial Lactate Concentration	—

Countries

Germany

Contacts

Public ContactThomas Walther

Uniklinikum Frankfurt, Klinik für Herz- und Gefäßchirurgie

thomas.walther@unimedizin-ffm.de+49 69 6301 3724

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026