I35.0 I48.2
Conditions
Interventions
Group 1: Patients with LG-AKS (KÖF = 1 cm² / MPG < 40 mmHg) and VHF are undergo invasive diagnostics via right/left heart catheterization. This involves simultaneous LV/Ao pressure measurement using t
Sponsors
Klinikum Byreuth
Eligibility
Sex/Gender
All
Age
19 Years to No maximum
Inclusion criteria
Inclusion criteria: - Patients with echocardiographically proven LG-AKS (AVA = 1qcm (valve orifice area), MPG 50% or LVEF < 50%). - Atrial fibrillation. - Patients in whom a cardiac-CT is indicated to measure the Agatston score.
Exclusion criteria
Exclusion criteria: - AVA > 1 qcm, MPG = 40mmHg. - Patients in whom simultaneous LV-Ao pressure measurement is not possible due to access problems. - Inadequate analysis of pressure curves. - LVOT obstruction. - Unstable patients (tachycardia, hypotension, angina...). - Mechanical aortic valve replacement. - Untreated relevant coronary heart disease (e.g. severe coronary three-vessel disease, significant left main stenosis, proximal LAD stenosis, high-grade ostial stenosis, ...). - Detection of thrombi in the left ventricle or in the left atrium/-atrial appendage. - Patients in whom a cardiac-CT is not indicated to measure the Agatston score.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is a PESP-PG = 40mmHg, which is measured invasively as follows: A VES is induced using a pigtail catheter (in the LV). The measurement is performed via simultaneous LV/Ao pressure registration and is analyzed using hemodynamic software (Siemens). | — |
Secondary
| Measure | Time frame |
|---|---|
| no secondary endpoints | — |
Countries
Germany
Contacts
Public ContactTaki Eddine Sid
Klinikum Bayreuth
Outcome results
None listed