Personalized digital training to enhance personality functioning during psychotherapy for depression: Conceptualization of an exploratory clinical trial (PERFUNC-CONCEPT)

Personalized digital training to enhance personality functioning during psychotherapy for depression: Conceptualization of an exploratory clinical trial (PERFUNC-CONCEPT) - PERFUNC-CONCEPT

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00034953

Enrollment

Registered

2025-12-22

Start date

2025-04-01

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F32 F33

Interventions

Group 1: conventional treatment (TAU) Group 2: conventional treatment (TAU) + digital PERFUNC intervention

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - PHQ = 5 (screening) - HAM-D = 17 - SCID-5-CV: DSM-5 depressive disorder (major/minor episode, persistent depressive disorder) - LPFS-BF = 15 (screening examination) - at least a moderately impaired level of personality functioning - at least a moderately impaired level of personality according to STiP assessment - written informed consent after explanation - Possession of a smartphone

Exclusion criteria

Exclusion criteria: - Insufficient German language skills - Bipolar disorder - Substance abuse with current consumption behavior - Psychotic disorders - Indication for a different treatment setting (outpatient therapy, treatment in closed psychiatric care)

Design outcomes

Primary

Measure	Time frame
- Objective 1: Feasibility assessment including evaluation of recruitment and dropout rates, intervention usage, daily monitoring, and the planned qualitative interviews - Objective 2: Between-group differences in depressive symptoms (PHQ-9) at discharge (t2)	—

Secondary

Measure	Time frame
Secondary outcomes at discharge t2: - OPD-Structural Questionaire (OPD-SF) - Outcome-Fragebogen 45 (OQ-45) - Mental Health Quality of Life Questionnaire (MHQoL) - Difficulties in Emotion Regulation Scale (DERS) - Certainty About Mental States Questionnaire (CAMSQ) - Barratt-Impulsivität-Skala (BIS) - Changes in daily monitoring Secondary Outcomes at follow-up(t3): - Depression (PHQ-9) - OPD-Structural Questionaire (OPD-SF) - Outcome-Fragebogen 45 (OQ-45) - Mental Health Quality of Life Questionnaire (MHQoL) - Difficulties in Emotion Regulation Scale (DERS) - Certainty About Mental States Questionnaire (CAMSQ) - Barratt-Impulsivität-Skala (BIS) - Changes in daily monitoring	—

Measure

Time frame

Secondary outcomes at discharge t2: - OPD-Structural Questionaire (OPD-SF) - Outcome-Fragebogen 45 (OQ-45) - Mental Health Quality of Life Questionnaire (MHQoL) - Difficulties in Emotion Regulation Scale (DERS) - Certainty About Mental States Questionnaire (CAMSQ) - Barratt-Impulsivität-Skala (BIS) - Changes in daily monitoring Secondary Outcomes at follow-up(t3): - Depression (PHQ-9) - OPD-Structural Questionaire (OPD-SF) - Outcome-Fragebogen 45 (OQ-45) - Mental Health Quality of Life Questionnaire (MHQoL) - Difficulties in Emotion Regulation Scale (DERS) - Certainty About Mental States Questionnaire (CAMSQ) - Barratt-Impulsivität-Skala (BIS) - Changes in daily monitoring

—

Countries

Germany

Contacts

Public ContactUlrike Dinger-Ehrenthal

ulrike.dinger-ehrenthal@lvr.de+49 211 922-4700

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026