Nociception and microcirculation
Conditions
Interventions
Group 1: The microcirculation in the palm is measured in all healthy participants while three stimuli are applied one after the other for five minutes each. The stimuli are PinPrick stimulators from q
Sponsors
Universitätsklinikum Heidelberg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Ability of subject to understand character and individual consequences of the study - Written informed consent
Exclusion criteria
Exclusion criteria: - Pain medication in the last 7 days - Medication that changes skin perfusion in the last 7 days - Expected lack of compliance or language barriers - Impossible measurement (Immobility, Protheses, Tattoo) - Pregnancy or breastfeeding - History of chronic pain - Pre-existing vascular disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary aim is to explore, if pain leads to a change in perfusion, which is measurable as a StO2 or NIR change of the palm. | — |
Secondary
| Measure | Time frame |
|---|---|
| A secondary aim is to explore, if pain leads to a change in perfusion, which leads to an altered absorbance spectrum of the palm. | — |
Countries
Germany
Contacts
Public ContactJan Larmann
Universitätsklinikum Heidelberg
Outcome results
None listed