Indications and preoperative-assessment of patients undergoing major lower extremity amputations: a retrospective comparative two-center cohort study

Indications and preoperative-assessment of patients undergoing major lower extremity amputations: a retrospective comparative two-center cohort study - AmpuLE

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00034914

Enrollment

400

Registered

2024-12-02

Start date

2025-01-01

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Amputation of Lower Extremity (OPS 5-864.x)

Interventions

Group 1: primary major lower extremity amputations conducted at Odense University Hospital (Denmark) Group 2: primary major lower extremity amputations conducted at University Hospital Freiburg (Germa

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Primary major lower extremity amputations between 1/2 2022 - 28/2 2024 conducted at University medical center Freiburg or Odense University Hsopital

Exclusion criteria

Exclusion criteria: age under 18, already had an amputation on the same limb, uncomplete data

Design outcomes

Secondary

Measure	Time frame
Pre-operative Imaging (CT-angiography, MR-angiography, other, none) Results of Imaging (kind of stenosis, number) Prior vascular surgery (number, open/closed procedure, central/peripheral) Complications after index-surgery Mortality after 30 days/ 1 year Re-amputation after 30 days/ 1 year	—

Primary

Measure	Time frame
Indications (acute ischemia, chronic ischemia, infection, oncology, trauma, other)	—

Countries

Denmark, Germany

Contacts

Public ContactJohanna Kubosch

Universitätsklinikum Freiburg, Klinik für Orthopädie und Unfallchirurgie

johanna.kubosch@uniklinik-freiburg.de+49 761 270 74940

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 28, 2026