P22.0 J80
Conditions
Interventions
Group 1: Neonatal or pediatric ARDS (nARDS/ pARDS) which meets the PALICC-2 or Montreux definition . Need for prolonged invasive mechanical ventilation (>24h). Gestational age >38+0 weeks, bodyweight
Sponsors
Uniklinikum Bonn, Klinik für Neonatologie und Pädiatrische Intensivmedizin, Eltern-Kind-Zentrum Bonn
Eligibility
Sex/Gender
All
Age
0 Years to 18 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria nARDS/pARDS group: - pediatric patients with respiratory failure (nARDS/pARDS and need for intubation with mechanical ventilation >24h - Weight =3.5 kg and/or chest circumference =36 cm - Consent of the parents to participate in the study
Exclusion criteria
Exclusion criteria: Exclusion criteria nARDS/ pARDS group: - Children with palliative care - Lack of parental consent - Contraindication against the performance of an EIT according to approval (e.g. pacemaker).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Identification of the best EIT-PEEP according to the EIT-derived Compliance (C EIT). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures were as follows: identification of further EIT- indices (global inhomogeneity index [GI] and center of ventilation [COV] as well as measurement of the respirator derived compliance (Cdyn). Furthermore duration of mechanical ventilation, ventilator free days after 28 days, inhospital-mortality. | — |
Countries
Germany
Contacts
Public ContactLukas Schröder
Uniklinikum Bonn, Klinik für Neonatologie und Pädiatrische Intensivmedizin, Eltern-Kind-Zentrum, Bonn
Outcome results
None listed