No diseases/health problems are examined
Conditions
Interventions
Group 1: 30 participants.
All participants are medical examined before start of the test session.
All participants are examined in an approx. 60-minute lasting session.
In test cycle A, after a dark
Sponsors
Uniklinik RWTH Aachen
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: - healthy subjects (n=30) - written informed consent - Participation in study "Differential effects of perseverative cognition on recovery from acute stress in a virtual reality environment" (EK 23-320)
Exclusion criteria
Exclusion criteria: - Participants with epilepsy, diseases of the peripheral nerves or other neurological diseases (e.g., migraine, post-apoplexy, cerebral hemorrhage, neurodegenerative diseases) - Particiants with severe eye diseases (e.g. glaucoma, retinal detachment, pupillary motor disorders) - Patients with mental illnesses - Participants with metabolic disorders (e.g. diabetes mellitus) - Participants who are taking medication that affects their ability to react and concentrate (e.g. painkillers from level II according to WHO) - Drug and/or alcohol abuse - Visible head injuries or diseases in the area of the head - Artificial eye lenses or the absence of an eye lens - Pregnant, breastfeeding and underage test subjects (< 18 years) - Skin diseases or sensory disorders of the feet - Polyneuropathy - Severe peripheral arterial occlusive disease - Raynaud's syndrome - Persons with syncope - Persons suffering from respiratory diseases (asthma)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary objective is to test the predictability of the individual stress response to psychosocial stress by assessing the parameters of the PLR under a cold-induced moderate pain stimulus (ice bath) compared to a warm foot bath. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary aim of the present study is to investigate whether induced acute stress (pain stimulus) can be identified by breath analysis and whether VOCs and/or NO have the potential to act as biomarkers that both recognize and differentiate stress. | — |
Countries
Germany
Contacts
Public ContactMichael Kursawe
Uniklinik RWTH Aachen
Outcome results
None listed