Evaluation Of Change in Corneal Biomechanics Following Non-Penetrating Deep Sclerectomy compared to Trabeculectomy or Paul-Implant in Glaucoma Patients: Insights From Ocular Response Analyzer (ORA) Measurements

Evaluation Of Change in Corneal Biomechanics Following Non-Penetrating Deep Sclerectomy compared to Trabeculectomy or Paul-Implant in Glaucoma Patients: Insights From Ocular Response Analyzer (ORA) Measurements - Biomechanics after glaucoma surgery

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00034870

Enrollment

160

Registered

2025-03-19

Start date

2024-10-07

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H40.1

Interventions

Group 1: Patients who undergo a deep sclerectomy Pre- and post-operative examinations of patients using ORA. The Ocular Response Analyzer (ORA) measures ocular hysteresis, providing important data on

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with primary open-angle glaucoma, pseudoexfoliation glaucoma, pigment dispersion glaucoma and (with Paul tube implants) secondary glaucoma

Exclusion criteria

Exclusion criteria: Non-consenting adults (= 18 years), children and adolescents (< 18 years), others (e.g. persons in closed institutions / in prison)

Design outcomes

Primary

Measure	Time frame
Visualization of the change in corneal hysteresis in comparison of pre- and postoperative values with different intraocular pressure-lowering procedures	—

Secondary

Measure	Time frame
Name clinical outcomes: - Corneal hysteresis - Visual field defects - Intraocular pressure - Number of pressure-reducing eye drops - Axis length - Nerve fiber layer thickness - visual acuity Differences between different types of surgery (bulb-opening procedures, non-bulb-opening procedures and drainage implants)	—

Countries

Germany

Contacts

Public ContactKarl Mercieca

Universitäts-Augenklinik Bonn

karl.mercieca@ukbonn.de+49(0)228/287-11515

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026