Postoperative ileus following emergency surgical treatment of acute intestinal obstruction: a case-control study of possible predictors and effects on postoperative recovery

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00034851

Enrollment

466

Registered

2024-08-13

Start date

2022-04-15

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K91.3

Interventions

Group 1: Patients who developed a postoperative ileus (POI) following emergency treatment of a mechanical bowel obstruction.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: intraoperative confirmation of a complete mechanical obstruction of the bowel lumen

Exclusion criteria

Exclusion criteria: - patients for whom the suspicion of mechanical bowel obstruction was not confirmed intraoperatively - chronic bowel adhesions leading to to incomplete stenosis of the bowel, treated by electively scheduled adhesiolysis - unavailable data regarding postoperative bowel function - patients receiving non-surgical interventions, such as endoscopic stent placement or percutaneous gastrostomy, as a palliative relief for the intestinal obstruction.

Design outcomes

Primary

Measure	Time frame
The primary endpoint was the development of postoperative ileus (POI), defined as the need for intravenous stimulation of bowel peristalsis with metoclopramide and neostigmine after the failure of other measures such as the administration of laxatives or oral Gastrografin.	—

Secondary

Measure	Time frame
Secondary outcome measures are: - duration of intensive care unit (ICU) stay - in-hospital mortality - postoperative morbidity, including both surgical (deep and superficial surgical site infections, revision surgery) and medical complications, with a focus on respiratory issues (postoperative pneumonia, need for non-invasive ventilation after extubation, need for reintubation) - requirement for supplemental caloric intake through parenteral nutrition - delayed removal of the nasogastric tube beyond postoperative day 3 - readmission rate to the ICU - rate of successful discharge to the initial home environment	—

Measure

Time frame

Secondary outcome measures are: - duration of intensive care unit (ICU) stay - in-hospital mortality - postoperative morbidity, including both surgical (deep and superficial surgical site infections, revision surgery) and medical complications, with a focus on respiratory issues (postoperative pneumonia, need for non-invasive ventilation after extubation, need for reintubation) - requirement for supplemental caloric intake through parenteral nutrition - delayed removal of the nasogastric tube beyond postoperative day 3 - readmission rate to the ICU - rate of successful discharge to the initial home environment

—

Countries

Germany

Contacts

Public ContactAnca-Laura Amati

Klinik für Allgemein-, Viszeral-, Thorax- und Transplantationschirurgie, Universitätsklinikum Gießen

Anca-Laura.Amati@chiru.med.uni-giessen.de+49 641 985 58748

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026