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Longitudinal Cohort Study of Idiopathic Intracranial Hypertension

Longitudinal Cohort Study of Idiopathic Intracranial Hypertension - GUIDANCE

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00034829
Enrollment
50
Registered
2024-08-13
Start date
2025-10-01
Completion date
Unknown
Last updated
2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G93.2

Interventions

Group 1: consecutive patients with idiopathic intracranial hypertension (IIH) and healthy controls will be compared regarding 1) structural changes (brain MRI and retinal imaging), 2) immunologic func

Sponsors

Experimental and Clinical Research Center - Charité Universitätsmedizin Berlin - Campus Buch
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Ability to give inform consent - presence of health insurance (in case of incidental findings) - signed informed consent for the patient cohort: - diagnosis of IIH according to modified Friedman criteria (Neurology, 2013, Friedman et al.) for the control cohort: - BMI and sex matched healthy subjects without signs of symptoms of IIH

Exclusion criteria

Exclusion criteria: - contraindications for MRI - pregnant women - diagnosis of secondary intracranial hypertension - severe psychiatric disorders or severely reduced health resulting in disability to complete testing

Design outcomes

Primary

MeasureTime frame
Detailed description of cohort characteristics and longterm clinical course in a IIH patient cohort, in comparison to healthy controls.

Secondary

MeasureTime frame
The relationship between structural changes in IIH and disease-related impairment.

Countries

Austria, Germany, Switzerland

Contacts

Public ContactTheresia Knoche

Charité Universitätsmedizin Berlin - Klinik für Neurologie - Campus Virchow Klinikum

theresia.knoche@charite.de+49 30 450 660 038

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026