Manifest type 2 diabetes with and without metabolically associated fatty liver disease ICD-10-E11 ICD-10-K76.0
Conditions
Interventions
Group 1: Patients with type 2 diabetes mellitus with metabolic dysfunction-associated steatotic liver disease (MASLD)
Patients with type 2 diabetes mellitus recruited by the Bochum Diabetes and Liver
Sponsors
Universitätsklinikum Knappschaftskrankenhaus Bochum Medizinisch Klinik
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Manifest type 2 diabetes, stable type 2 diabetes controlled with medication (>3 months)
Exclusion criteria
Exclusion criteria: Refusal of consent, unstable type 2 diabetes, risk of metabolic derailment, active malignant diseases in the last 5 years, any chronic inflammatory disease of the intestine (e.g. Crohn's disease, ulcerative colitis)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evidence of an association of exercise behavior with the occurrence of metabolic dysfunction-associated steatotic liver disease in type 2 diabetes. | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation with parameters of liver function and glucose and lipid metabolism, the concentration of metabolites and cytokines associated with fatty liver disease in the blood and stool, parameters of the intestinal microbiome and bile acid balance, as well as psychosocial correlation in everyday life in connection with exercise behavior. | — |
Countries
Germany
Contacts
Public ContactAnna Vogelsang
Ruhr-Universität Bochum Fakultät für Sportwissenschaft
Outcome results
None listed