MEdial Retropharyngeal Lymph node Involvement in non-endemic Nasopharyngeal carcinoma

MEdial Retropharyngeal Lymph node Involvement in non-endemic Nasopharyngeal carcinoma - MERLIN

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00034782

Enrollment

373

Registered

2025-01-03

Start date

2025-04-24

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C11

Interventions

Group 1: Retrospective multi-center analysis of patients treated between 2004 and 2023 for nasopharyngeal carcinoma

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - histopathologically confirmed diagnosis of nasopharyngeal cancer in patients living in a non-endemic region - pretherapeutic imaging includes MRI or PET-CT-scan - 3D planned radiotherapy - treatment between 01/2004 and 12/2023 - at least 12 months of follow-up

Exclusion criteria

Exclusion criteria: At least one inclusion criteria is not fulfilled.

Design outcomes

Primary

Measure	Time frame
Involvement of medial retropharyngeal lymph nodes is a binary variable and the primary endpoint of this study.	—

Secondary

Measure	Time frame
- Overall survival, progression-free survival, distant metastases free survival - Pattern of recurrence - Radiation treatment (dose and fractionation, boost yes/no?) - Chemotherapy (concurrent/neoadjuvant/regimen) - Treatment duration - Toxicity	—

Countries

Germany

Contacts

Public ContactJustus Kaufmann

Klinik und Poliklinik für Radioonkologie und Strahlentherapie

Justus.Kaufmann@unimedizin-mainz.de06131 17 3851

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 18, 2026