U07.1
Conditions
Interventions
Group 1: The population was defined as the population subject to social insurance contributions in Germany aged 18 and over (n=300-1000) working in critical infrastructure facilities and companies in
Sponsors
Betriebsärztlicher Dienst Universitätsklinikum Bonn
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Employees are recruited who are exposed to a high risk of infection with relevant SARS-CoV-2 variants due to their professional activities in facilities and have been immunized.
Exclusion criteria
Exclusion criteria: Non aplicable.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| a. Humoral and cellular immunity: n=30: SARS-CoV-2-S1-specific B and T memory cells 1. n=300-1000 plaque reduction neutralization test 2. anti-spike IgG-AK 2. anti-nucleocapsid IgG-AK 3. saliva anti-spike IgG-AK | — |
Secondary
| Measure | Time frame |
|---|---|
| b. Incidence of SARS-CoV-2 infections using qualitative questionnaires Uniklinik Bonn c. Qualitative determination of the physical activity of the test subjects using a questionnaire -Freiburg Questionnaire on Physical Activity d. Quantitative determination of physical activity using bicycle ergometry: power output, heart rate, blood pressure | — |
Countries
Germany
Contacts
Public ContactWerner Monzón Posadas
VIR-IMMUNE Präventionsforschung
Outcome results
None listed