F00 G20 F01
Conditions
Interventions
Group 1: Patients with a diagnosis of Alzheimers disease, Parkinson's disease or vascular cognitive impairment as well as healthy control subjects will be included. After sufficient time for reflectio
Sponsors
Uniklinik RWTH Aachen
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Diagnosis of Alzheimer´s disease (AD), Parkinson’s disease (PD), vascular cognitive impairment (VCI) according to current national and international diagnostic criteria guidelines (S3 Demenz Leitlinien)
Exclusion criteria
Exclusion criteria: Inability to consent based on severity of cognitive impairment, as defined by a stage of moderate to severe dementia, defined by a Clinical Dementia Rating (CDR) total score >=2, according to clinical records. For the healthy (neurotypical) control group: history of past or current neurological or major psychiatric disorder, severe traumatic brain injury, alcohol or drug abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Use of automatically extracted natural language processing (NLP)-derived features from spontaneous speech to recognise cognitive impairment associated with Alzheimer's disease and related dementias (ADRDs). | — |
Secondary
| Measure | Time frame |
|---|---|
| Characterise ADRDs using language features that differ significantly from those of neurotypical populations. | — |
Countries
Germany
Contacts
Public ContactKathrin Reetz
Uniklinik RWTH Aachen
Outcome results
None listed