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Comparison of various radiation-free methods for attenuation correction (AC) in pediatric examinations on the Biograph Vision Quadra (PET/CT)

Comparison of various radiation-free methods for attenuation correction (AC) in pediatric examinations on the Biograph Vision Quadra (PET/CT) - CTfreeAC

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00034723
Enrollment
20
Registered
2024-07-26
Start date
2024-08-30
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

various oncological diseases

Interventions

Group 1: Children/adolescents in whom an additional dose-neutral attenuation correction (LSO-TX) is performed on clinically indicated PET/CT for CT-based attenuation correction. Group 2: Children/adol

Sponsors

Radiologische Universitätsklinik Tübingen, Abteilung für Diagnostische & Interventionelle Radiologie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 17 Years

Inclusion criteria

Inclusion criteria: Children/adolescents <18 years of age who have undergone a whole-body MRI and are to undergo a PET scan with the Biograph Vision Quadra for clinical indications (usually staging and restaging, risk stratification for malignant tumours), or children/adolescents aged <18 years who are to undergo a clinically indicated PET/MRI and who also require a high-contrast, low-dose CT scan of the lungs and bones for clinical indications, or children/adolescents aged <18 years who are to undergo a clinically indicated PET scan, but who also require a low-dose CT scan for morphological classification of the expected findings. In addition, written consent should always be obtained from the legal guardian and, if appropriate, the child.

Exclusion criteria

Exclusion criteria: pregnancy

Design outcomes

Primary

MeasureTime frame
Feasibility of three different radiation-free methods for attenuation correction of long-axial field PET/CT in pediatric patients (LSO-TX, MR-Reg, Synthetic-AI CT)

Secondary

MeasureTime frame
Establishment of PET measurement protocols for pediatric patients without CT-induced dose

Countries

Germany

Contacts

Public ContactJürgen Schäfer

Radiologische Universitätsklinik Tübingen, Abteilung für Diagnostische & Interventionelle Radiologie

juergen.schaefer@med.uni-tuebingen.de49(0)7071-29-85637

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: May 1, 2026