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Characteristics of BRAF Mutations Across Entities

Characteristics of BRAF Mutations Across Entities - CoBRA

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00034636
Enrollment
200
Registered
2024-10-21
Start date
2024-10-28
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malignant diseases (hematological and onocological) linked to BRAF or other RAF (RAF1, ARAF) mutations

Interventions

Group 1: Patients with diagnosis of a cancer with an alteration in BRAF or related genes (ARAF, RAF1) referred to the molecular tumorboard at any of the participating ZPM sites, irrespective of cancer

Sponsors

Universitätsklinikum Freiburg, Klinik für Innere Medizin 1
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: o Diagnosis of a cancer with an alteration in BRAF or related genes referred to the MTBs at any of the above mentioned ZPM site, irrespective of cancer entity. o Patient’s written consent is available.

Exclusion criteria

Exclusion criteria: - Denial or withdrawal of written consent. - mutation which cannot be linked to any manifestation of malignancy as judged from a bioinformatical and molecular medicine perspective

Design outcomes

Primary

MeasureTime frame
Overall Survival after standard of care treatment and personalized treatment recommendations.

Secondary

MeasureTime frame
Progression free survival after standard of care treatment and personalized treatment recommendations.

Countries

Germany

Contacts

Public ContactKhalid Shoumariyeh

Universitätsklinikum Freiburg, Klinik für Innere Medizin 1

khalid.shoumariyeh@uniklinik-freiburg.de0761 270-34010

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026