Impact of diet on the immune system
Conditions
Interventions
Group 1: Study subjects under milk-free diet
A venous blood sample will be collected at baseline, i.e. , 40 ml of herparinized blood and 10 ml of serum. We will examine the blood for the reactivity o
Sponsors
Universitätsklinikum Bonn
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: none
Exclusion criteria
Exclusion criteria: - autoimmune or neurological diseases - proven gluten intolerance
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| • Evidence of milk-reactive antibodies in the peripheral blood • Evidence of an effect of cow's milk consumption on pro- and anti-inflammatory immune responses depending on the existence of a milk-specific immune response when entering the study | — |
Secondary
| Measure | Time frame |
|---|---|
| • Milk-specific antibody titers before and after cow's milk consumption • Change in the percentage distribution of pro and anti-inflammatory immune cell populations before and after cow's milk consumption • Change of the permeability of the intestinal barrier before and after cow's milk consumption • Change of microbiome composition before and after cow's milk consumption | — |
Countries
Germany
Contacts
Public ContactStefanie Kürten
Universitätsklinikum Bonn
Outcome results
None listed