Automatic segmentation of vestibular schwannomas using Deep Neural Patchwork and correlation to its clinical symptoms (hearing loss, vertigo and tinnitus)

Automatic segmentation of vestibular schwannomas using Deep Neural Patchwork and correlation to its clinical symptoms (hearing loss, vertigo and tinnitus) - AKN_Seg_DNP

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00034593

Enrollment

400

Registered

2024-07-25

Start date

2024-01-29

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

D33.3

Interventions

Group 1: All patients that have been diagnosed or treated with vestibular schwannoma (VS) at university hospital Freiburg since 2008. Excluded were: - all patients with neurofibromatosis type II - pat

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: MR image in T1 present vestibular schwannoma has been diagnosed

Exclusion criteria

Exclusion criteria: postoperative patients patients with neurofibomatosis type II no sufficient information about the patient available

Design outcomes

Primary

Measure	Time frame
Average Dice-Score of DNP-segmentation and manual segmentation. Correlation of symptoms (occurrence and intensity) with DNP-segmentated volume of vestibular schwannoma. Is a larger volume of an acoustic neuroma associated with a higher frequency or greater intensity of symptoms such as hearing loss, vertigo and tinnitus?	—

Secondary

Measure	Time frame
Which frequency is most affected by hearing loss by the growth of an acoustic neuroma? How strongly does the segmented AN volume correlate with the results of brainstem evoked response audiometry? Can automated segmentation of vestibular schwannoma give us information about the likelihood of occurence and intensity of symptoms? How ist growth of acoustic neuroma ifluenced by stereotaktic radiotherapie? Do Gender, Age or side of the AN korrelate with size and growth rate of AN?	—

Measure

Time frame

Which frequency is most affected by hearing loss by the growth of an acoustic neuroma? How strongly does the segmented AN volume correlate with the results of brainstem evoked response audiometry? Can automated segmentation of vestibular schwannoma give us information about the likelihood of occurence and intensity of symptoms? How ist growth of acoustic neuroma ifluenced by stereotaktic radiotherapie? Do Gender, Age or side of the AN korrelate with size and growth rate of AN?

—

Countries

Germany

Contacts

Public ContactAnn-Kathrin Rauch

Universitätsklinikum Freiburg, Klinik für Hals-, Nasen- und Ohrenheilkunde

ann-kathrin.rauch@uniklinik-freiburg.de+49 (0)761/270-42010

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026