patients with simple mastectomy or skin-sparing mastectomy
Conditions
Interventions
Group 1: general anesthesia (control group)
Group 2: general anesthesia + regional anesthesia, i.e. Pectoralis nerve and serratus plane nerve blocks (PECS II)
Group 3: general anesthesia + regional an
Sponsors
Charité - Universitätsmedizin Berlin, Klinik für Gynäkologie mit Brustzentrum
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - written consent; - ASA I-III; - elective procedure N5: prophylactic ablatio simplex and/or skin-sparing mastectomy
Exclusion criteria
Exclusion criteria: - ASA IV and V - BMI >40 kg/m2 - Patients with emergency interventions (N4 +) - Refusal to participate in the study - Hypersensitivity to local anesthetics - Contraindication to one of the analgesia procedures - Previous scoliosis operations - Chronic pain patient - Presence of myasthenia gravis - Alcohol abuse - Lack of willingness to store and pass on pseudonymized medical data as part of the study - Patient is institutionalized by court or official order or currently unable to give consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of recovery (QoR-15GE) | — |
Secondary
| Measure | Time frame |
|---|---|
| perioperative processes; total dose of opioids administered postoperatively (cumulative morphine equivalents); health-related quality of life (PROMIS-33); quality of life (QLQ-C30); quality of life in breast cancer (QLQ-BR23); pain (subscales from the German pain questionnaire); overall patient satisfaction with pain therapy; intraoperative complications according to ClassIntra; postoperative complications according to Clavien-Dindo | — |
Countries
Germany
Contacts
Public ContactMaria Margarete Karsten
Charité - Universitätsmedizin Berlin, Klinik für Gynäkologie mit Brustzentrum
Outcome results
None listed