Environmental tobacco smoke as a risk factor for the development of oral squamous cell carcinoma – a multicentric case-control-study (PROSCC)

Environmental tobacco smoke as a risk factor for the development of oral squamous cell carcinoma – a multicentric case-control-study (PROSCC) - PROSCC

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00034483

Enrollment

800

Registered

2024-06-17

Start date

2024-12-02

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C02 C03 C04 C05 C06

Interventions

Group 1: cases: patients with histological confirmed oral squamous cell carcinoma (OSCC), controls: patientes without OSCC

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Case group: Biopsy-proven oral squamous cell carcinoma Age > 18 years existing capacity to consent Control group: No diagnosed oral squamous cell carcinoma Age > 18 years existing capacity to consent not a family member 1° of a case

Exclusion criteria

Exclusion criteria: Case group: Oro-, naso- hypopharyngeal carcinoma, lip carcinoma History of other malignant disease Age < 18 years no existing capacity to consent Immunosuppression Control group: Age < 18 years no existing capacity to consent History of malignant disease Immunosuppression Family member 1° of a case

Design outcomes

Primary

Measure	Time frame
ETS Score (ETS = environmental tobacco smoke), OR (Odds ratio)	—

Secondary

Measure	Time frame
corresponding clinical and histopathological characteristics	—

Countries

Germany

Contacts

Public ContactSusanne Wolfer

Universitätsmedizin Göttingen

susanne.wolfer@med.uni-goettingen.de+4917641096123

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Sep 19, 2026