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A study to determine possible etiological links between biological factors and dentofacial phenotypes

A study to determine possible etiological links between biological factors and dentofacial phenotypes

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00034466
Enrollment
1050
Registered
2024-06-13
Start date
2024-07-01
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with dentofacial phenotypes

Interventions

Group 1: Children, adolescents and adults undergoing orthodontic treatment at the Polyclinic for Orthodontics at Bonn University Hospital or in participating practices and who have given informed cons

Sponsors

Universitätsklinikum Bonn, Poliklinik für Kieferorthopädie
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The informed patient and, in the case of minors, their legal guardians must have consented to participate in the study. The diagnostic documents which are relevant for the individual examinations (outcomes) must be available and have been prepared as part of a medically indicated dental-orthodontic diagnosis and treatment. An exception is the saliva sample to be obtained as part of the study. In addition, only systemically healthy patients or patients with mild systemic and well-controlled diseases should be included in the study.

Exclusion criteria

Exclusion criteria: Patients with serious systemic diseases and known genetic and non-genetic syndromes as well as traumas or operations in the head and neck area

Design outcomes

Primary

MeasureTime frame
- Evaluation of the molecular and clinical aspects related to the phenotypes of normal tooth development and the phenotypes of developmental tooth changes - Investigation of the clinical and genetic factors that influence the tooth age - Investigation of the molecular factors and clinical factors involved in the development of adverse side effects of orthodontic treatment.

Countries

Germany

Contacts

Public ContactChristian Kirschneck

Universitätsklinikum Bonn, Poliklinik für Kieferorthopädie

kfo.sekretariat@ukbonn.de+4922828722449

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 14, 2026