Exhaled biomarkers in patients with acute heart failure

Exhaled biomarkers in patients with acute heart failure - BREATHE

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00034455

Enrollment

100

Registered

2024-06-11

Start date

2024-09-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with and without acute heart failure

Interventions

Group 1: Patients with acute heart failure Patients with the stated inclusion criteria (acute heart failure) are approached about participating in the study. The study idea and the principle of the br

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: -Acute heart failure as inpatient admission diagnosis, clinical signs of fluid overload/decompensation, NT-proBNP >1,800 pg/ml -Control group: cardiological diagnosis with the exception of acute heart failure, NT-proBNP value < 300 pg/ml; recruitment takes place both as an inpatient and via the university cardiology outpatient clinic

Exclusion criteria

Exclusion criteria: -Severe impairment of lung function with inability to perform a slow exhalation maneuver -Lack of cooperation or legal capacity of the patient -Lack of consent

Design outcomes

Primary

Measure	Time frame
Accuracy of detection of the diagnosis of acute heart failure Results of the test accuracy (AUC-ROC, sensitivity, specificity, positive predictive value, negative predictive value) are to be determined.	—

Countries

Germany

Contacts

Public ContactAnja Haase-Fielitz

Medizinische Hochschule Brandenburg

anja.haase-fielitz@mhb-fontane.de03338694649

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 9, 2026