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Observational study of in vivo forces and musculoskeletal loading conditions in fracture healing

Observational study of in vivo forces and musculoskeletal loading conditions in fracture healing

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00034409
Enrollment
30
Registered
2024-06-05
Start date
2024-08-09
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

S82.1 S82.2 S82.3 S82.7 S72

Interventions

Group 1: In patients with osteosynthetically treated fractures of the long bones, the healing process is monitored radiologically with motion analysis at the Charité (4-6 and 12-18 weeks postoperative

Sponsors

Charité - Universitätsmedizin Berlin, Julius Wolff Institut
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Adult, legally competent, all patients who understand and sign the consent form to participate in the study, fracture of the long bones (femur or tibia), osteosynthetic treatment, were mobile preoperatively.

Exclusion criteria

Exclusion criteria: Motor or other medical limitations that do not allow movement analysis, osteoporosis or cancer, non-attendance at examination appointments.

Design outcomes

Primary

MeasureTime frame
Assessment of healing quality using the radiographic score [modified Radiographic Union Score for Tibial Fractures (mRUST)] and measurement of interfragmentary motion in patients by fluoroscopy.

Secondary

MeasureTime frame
Clinical scores: PROMs [Visual analog scale (VAS), pressure pain, SF-36 / Knee Society Score (KSS)]; biomechanical function improvement: ground reaction forces [symmetry to contralateral], Short Physical Performance Battery [SPPB]).

Countries

Germany

Contacts

Public ContactAdam Trepczynski

Charité - Universitätsmedizin Berlin, Julius Wolff Institut

adam.trepczynski@bih-charite.de+49 30 450 559589

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026