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Influence of the dosage form and the patient-specific dosage on acceptance and the complexity of using oral dexamethasone in children and Adolescents as part of antiemetic prophylaxis during chemotherapy

Influence of the dosage form and the patient-specific dosage on acceptance and the complexity of using oral dexamethasone in children and Adolescents as part of antiemetic prophylaxis during chemotherapy

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00034275
Enrollment
21
Registered
2024-09-24
Start date
2025-01-17
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Antiemetic prophylaxis in the context of chemotherapy

Interventions

Group 1: In addition to their indicated chemotherapy, patients also receive dexamethasone as prophylaxis against nausea - During a cycle of chemotherapy in the form of commercial tablets (dosage if ne

Sponsors

Universitätsklinikum Hamburg-Eppendorf
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1. Pediatric patients aged six and over who are treated in the Clinic for Pediatric Hematology and Oncology at the University Hospital Hamburg-Eppendorf 2. Indication for at least two cycles of dexamethasone-containing antiemetic prophylaxis in a solid oral dosage form during chemotherapy

Exclusion criteria

Exclusion criteria: 1. Lack of written consent from patients and/or legal representatives 2. Lack of ability to participate in the survey (linguistic, cognitive)

Design outcomes

Primary

MeasureTime frame
1. Acceptance of drug therapy with dexamethasone in different pharmaceutical forms as part of antiemetic prophylaxis in children 2. Complexity of drug therapy (subjective and objective) with dexamethasone in various dosage forms as part of antiemetic prophylaxis with children

Secondary

MeasureTime frame
1. Assessment of parental acceptance 2. Acceptance at different ages 3. Complexity at different ages 4. Adherence to antiemetic prophylaxis with oral dexamethasone (number, timing)

Countries

Germany

Contacts

Public ContactWilhelm Wößmann

Universitätsklinikum Hamburg-Eppendorf

w.woessmann@uke.de+49-40-7410-20561

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 27, 2026