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Dissociable behavioral and neurophysiological mediators of cognitive behavioral therapy (CBT) and high intensity interval training (HIIT) success in cannabis use disorder

Dissociable behavioral and neurophysiological mediators of cognitive behavioral therapy (CBT) and high intensity interval training (HIIT) success in cannabis use disorder - TRR265 C03 / CANnaQUIT

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00034219
Enrollment
219
Registered
2024-07-12
Start date
2024-12-13
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cannabis Use Disorder (DSM-V)

Interventions

Group 1: CBT group. This group only receives cannabis-specific cessation psychotherapy over a period of 12 weeks. The group sessions take place once a week over a period of 90 minutes. Group 2: CBT +

Sponsors

Charité - Universitätsmedizin Berlin
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Diagnosed cannabis use disorder (DSM-V)

Exclusion criteria

Exclusion criteria: Acute (hypo-)manic episode remitted for less than 4 weeks Depressive episode remitted for less than 4 weeks Psychopharmacological treatment of bipolar disorder/ depressive episode less than 2 weeks stable Schizophrenia/ psychotic episode: fully remitted for less than 4 weeks Current psychotherapeutic or addiction-specific treatment (without possible break during the study) Taking sedatives/ neuroleptics/ stimulants Current other substance use disorder apart from nicotine & cannabis

Design outcomes

Primary

MeasureTime frame
Pupil size (Pupil Labs; objective and continuous measure) Skin conductance (PsychLab; objective and continuous measure) Heart rate (PsychLab; objective and continuous measure) Oxytocin reactivity (Salivette®; objective and continuous measure) Cannabis abstinence (Drug-Screen® Multi 7 Test; objective and categorical measure) Consumption reduction (Form-90 interview; subjective and continuous measure)

Secondary

MeasureTime frame
Depressiveness (BDI-II; Beck et al., 1996) (Social) Anxiety (LSAS; Liebowitz, 1987 and GAD-7; Spitzer et al., 2006) Physical activity (IPAQ; Craig et al., 2003) State of health (SF-12; Ware et al., 1996)

Countries

Germany

Contacts

Public ContactLivia Welsch

Charité - Universitätsmedzin Berlin

livia.welsch@charite.de+49 30 450 517 273

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026