C25
Conditions
Interventions
Group 1: Patients with clinical stage I-III resectable and borderline resectable pancreatic cancer (PDAC) scheduled for curative intent surgical resection
Sponsors
Universitätsklinikum Schleswig Holstein Campus Lübeck
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Age at least 18 years old and capable of signing informed consent - Patient deemed fit to undergo curative intent surgery and perioperative therapy - Indication for curative intent PDAC resection according to the German S3 guideline (PDAC histologically proven or CT imaging and further diagnostics (e.g. EUS, MRI, labs) highly suspicious of PDAC) - Resectable PDAC according to the German S3 guideline criteria (CT imaging and biological parameters) - Borderline resectable PDAC according to the German S3 guideline criteria (CT imaging and biological parameters)
Exclusion criteria
Exclusion criteria: - Second malignancy at the time of diagnosis of PDAC - Distant metastasis (M1) - Chemotherapy or radiotherapy already started - Patients with resectable disease who wish to undergo neoadjuvant therapy - Patient does not wish to receive perioperative therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body composition parameters (weight, diet, cachexia, motoric status) will be evaluated via CT-based assessment of already existing CT abdomen scans. | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient-reported quality of life (standardized validated questionnaire ED-5D-5L, EORTC-QLQ-C30, EORTC-QLQ-PAN26) in three month intervals after resection | — |
Countries
Germany
Contacts
Public ContactLouisa Bolm
Universitätsklinikum Schleswig-Holstein, Campus Lübeck
Outcome results
None listed