Skip to content

Retrospective analysis of radiotherapy plans for patients with brain metastases

Retrospective analysis of radiotherapy plans for patients with brain metastases

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00034150
Enrollment
2000
Registered
2024-12-20
Start date
2024-10-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C79.3

Interventions

Group 1: Patients who have undergone (adjuvant or definitive) radiotherapy for brain metastases.

Sponsors

Klinikum der Universität München
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: ? Definitive or postoperative percutaneous radiotherapy ? Single or multiple brain metastases ? Single or fractionated radiotherapy ? Re-irradiation

Exclusion criteria

Exclusion criteria: no

Design outcomes

Primary

MeasureTime frame
The primary objective is to analyse the extent of the radiation fields (especially the planning target volume (PTV)), compare it between the different patient cases and correlate it with the survival data (e.g. overall survival (OS)).

Secondary

MeasureTime frame
Secondary objectives include the identification of side effects such as the frequency of cerebral oedema and radionecrosis and comparison with the dose distribution. For this purpose, the irradiation exposure of the organs at risk (e.g. brain, brain stem, optic nerves) and the quality control with the corresponding constraints are to be analysed. In addition, an analysis of the different irradiation techniques (e.g. 3D plan, VMAT) will be carried out and, in particular, the side effect profiles and the failure rate will be analysed.

Countries

Germany

Contacts

Public ContactSebastian Maier

Klinikum der Universität München

sebastian.maier@med.lmu.de+49 89 4400 73770

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 9, 2026