Prospective randomized clinical trial: Surgical success rates in childhood glaucoma: Conventional probe trabeculotomy versus microcatheter-assisted 360°trabeculotomy

Prospective randomized clinical trial: Surgical success rates in childhood glaucoma: Conventional probe trabeculotomy versus microcatheter-assisted 360°trabeculotomy - PIRATE - Probe versus mIcrocatheteR Assisted TrabEculotomy

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00034139

Enrollment

Registered

2024-04-24

Start date

2024-05-23

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H40

Interventions

Group 1: Microcatheter-assisted trabeculotomy Group 2: Probe trabeculotomy

Eligibility

Sex/Gender

All

Age

0 Years to 17 Years

Inclusion criteria

Inclusion criteria: Main inclusion criteria: - Patients with primary or secondary congenital glaucoma in both eyes - Age = 17

Exclusion criteria

Exclusion criteria: Main exclusion criteria: - Indication other than trabeculotomy, e.g. glaucoma drainage device or cyclodestructive treatment - previous surgical IOP-lowering interventions (i.e. cataract surgery, vitrectomy etc. are allowed)

Design outcomes

Primary

Measure	Time frame
Complete surgical success at 24 months (IOP 120° is also required for success)	—

Secondary

Measure	Time frame
Incomplete surgical success (IOP < 18 mmHg, with medication and/or revision surgery), absolute and relative difference of: intraocular pressure (IOP), axial length, visual acuity, refraction, corneal diameters, cup-to-disc ratio; presence of Haab striae, number of medication drugs, number of revision surgeries, number of intraoperative and postoperative events	—

Countries

Belgium, Germany

Contacts

Public ContactEsther M. Hoffmann

Universitätsmedizin Mainz, Augenklinik

ehoffman@uni-mainz.de+49 6131 17 5150

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: May 1, 2026