F04
Conditions
Interventions
Group 1: This is a longitudinal study over a period of 12 months with the aim of improving the concept of risk reporting based on the ApoE gene status and investigating the needs of the target group.
Sponsors
Klinik und Poliklinik für Psychiatrie und Psychotherapie Uniklinik Köln (AöR)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Age at least 18 years - Informed, written consent of the study participants - sufficient knowledge of German to answer the questionnaires - previous participation in the INSPIRATION study (DRKS00020767) or lipid study (DRKS00031261) with determination of ApoE gene status - heterozygous or homozygous ApoE-e4 gene status
Exclusion criteria
Exclusion criteria: - Diagnosis of dementia - MMSE ¬= 27 points - moderate to severe depressive disorder - anxiety disorder - HADS score > 10 points - Acute suicidal tendencies -deficit of german language skills
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| This study examines how people who find out their personal dementia risk profile deal with this risk knowledge. To this end, a standardized methodology is being developed to determine how communication should take place before, during and after the disclosure of genetic status. A quantitative survey will be used to collect information on the effects of disclosing the individual risk on the test persons and what their needs are. The aim of the work is to develop a standardized information process for this risk group. All target variables are collected using questionnaires. | — |
Countries
Germany
Contacts
Public ContactAyda Rostamzadeh
Kölner Alzheimer Präventionszentrum, Uniklinik Köln
Outcome results
None listed