Prevalence of non-tuberculous infections in patients with presumed tuberculosis disease in Gabon – a proof-of-principle study

Prevalence of non-tuberculous infections in patients with presumed tuberculosis disease in Gabon – a proof-of-principle study - NoTB

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00034074

Enrollment

150

Registered

2024-06-06

Start date

2024-09-19

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A15.9

Interventions

Group 1: Patients with presumed tuberculosis disease presenting to CERMEL TB department within the study period (planned: 07/2024 -03/2025) and for whom attending physicians initiate a TB work-up. The

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Arm 1: presumptive pulmonary TB (including concurrent EPTB) consulting or referred to CERMEL tuberculosis laboratory for diagnostic TB work up (including microbiological investigations (TB-culture, TB-PCR) and lung imaging) Arm 2: healthy controls accompanying patients with presumed TB Arm 3: TB-healthcare providers at CERMEL

Exclusion criteria

Exclusion criteria: Arm 1: - No consent given - No TB work-up initiated by attending physician - Already under anti-TB treatment for >7 days Arm 2: - No consent given - TB work-up initiated by attending physician - TB diagnosed and/or under anti-TB treatment within past 6 months - Positive WHO-symptom screen for TB disease Arm 3: - does not agree with recording of interview

Design outcomes

Primary

Measure	Time frame
1. non-tuberculous lung infection prevalence (mycobacterial, non-mycobacterial, fungal and parasitic) in patients with presumed TB 2. contribution of non-tuberculous infections to disease outcomes per “confirmed” or “clinical TB” or “no TB diagnosed”	—

Secondary

Measure	Time frame
Exploration of perspectives regarding the diagnostic process across different types of cases (clinical TB, no diagnosis made, confirmed TB) and preferences for TB diagnostic services of patients and providers	—

Countries

Gabon

Contacts

Public ContactSabine Bélard

Universitätsklinikum Tübingen, Institut für Tropenmedizin

sabine.belard@uni-tuebingen.de+497071 29-82365

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026