Interaction of malignant cells and factors influencing tumour microenvironment

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00034065

Enrollment

228

Registered

2024-06-06

Start date

2023-03-09

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C92 C90.0 C81 C85 C96.8

Interventions

Group 1: Leukaemia, Lymphoma, Myeloproliferative neoplasm, Multiple myeloma, Histiocytosis and solid tumours. Planned line of investigations: Influence of malignant cells in tumor microenvironment, m

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Cancer patients providing consent

Exclusion criteria

Exclusion criteria: Patients not providing consent and minors

Design outcomes

Primary

Measure	Time frame
Determine if the tissue surrounding tumour cells exhibits a higher mutation rate compared to non-infiltrated tissue	—

Secondary

Measure	Time frame
Exploring the factors underlying the heightened mutation rate in adjacent tissue, encompassing genetic, metabolic, and proteomic changes. Additionally, the correlation between mutation rates in the stroma and patients' prognosis and outcomes will be investigated.	—

Countries

Germany

Contacts

Public ContactCyrus Khandanpour

Universitätsklinikum Schleswig-Holstein, Campus Lübeck

Cyrus.Khandanpour@uksh.de0049 451500 75621

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026