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Autogenous Tooth Transplantation of Canines - A Prospective Study on the Clinical Benefit of Adjunctive Antibiosis

Autogenous Tooth Transplantation of Canines - A Prospective Study on the Clinical Benefit of Adjunctive Antibiosis - TXAB

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00034011
Enrollment
60
Registered
2024-04-04
Start date
2021-10-21
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autogenous tooth transplantation

Interventions

Group 1: Subjects with intervention of an autogenous canine transplantation - without adjuvant antibiotic therapy Group 2: Subjects with intervention of an autogenous canine transplantation - with i

Sponsors

LMU Klinikum - Poliklinik für Zahnerhaltung und Parodontologie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
11 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.) Indication for autogenous transplantation of a displaced canine. This is given in cases of definite retention of the tooth, possibly after exhausting orthodontic treatment options. Clinical or radiological findings can include: total displacement with resorption of adjacent teeth, mechanical retention (for example, pronounced root hooks or impaction), delay of the physiological eruption time by more than two years, unsuccessful attempt at integration through exposure and bracketing (19–21). 2.) Patient consent (and parental consent for minors) 3.) Acceptable oral hygiene (Gingiva, plaque, and calculus index = 1) 4.) Patient age of at least 11 years

Exclusion criteria

Exclusion criteria: 1.) Psychomotor retardation with inability to consent 2.) Severe systemic illness (congenital/acquired), e.g., syndromal diseases or similar, unstable metabolic disorders, etc. 3.) Immunodeficiency (congenital/acquired/medication-associated) 4.) Current or past malignancy 5.) Chromosomal aberrations 6.) Severe coagulation disorders 7.) Bone diseases or ossification disorders 8.) Alcohol, narcotic, or medication abuse 9.) Heavy nicotine abuse (consumption of > 20 cigarettes/day) 10.) Use of cortisone, bisphosphonate, or denosumab derivatives 11.) Lack of compliance

Design outcomes

Primary

MeasureTime frame
Success rate of canine transplants two years postoperatively (assessed according to various clinical and radiological parameters)

Secondary

MeasureTime frame
Survival rate of the canine transplants two years postoperatively

Countries

Germany

Contacts

Public ContactKarin Huth

LMU Klinikum - Poliklinik für Zahnerhaltung und Parodontologie

Karin.Huth@med.uni-muenchen.de+49 89 44005 9411

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026