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Validation of artificial intelligence algorithms for the diagnosis of X-ray images in paediatric diagnostics

Validation of artificial intelligence algorithms for the diagnosis of X-ray images in paediatric diagnostics - LMU-RAD01186

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00033987
Enrollment
20000
Registered
2024-08-02
Start date
2024-07-10
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Presence of x-ray in pediatric/child surgical context

Interventions

Group 1: - Identification of specific patient cohorts and suitable control cohorts and/or clinically representative cohorts in a circumscribed retrospective period - Export and anonymisation of the u

Sponsors

Klinik und Poliklinik für Radiologie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years

Inclusion criteria

Inclusion criteria: 1. paediatric patient collective, i.e. all patients who are cared for by a paediatric or paediatric surgery/orthopaedic department of the LMU Clinic, usually age <= 18 years with exceptions (e.g. adult patients who are cared for by the CF outpatient clinic) 2. availability of X-ray images 3. the usual quality criteria of X-ray technology apply (e.g. pathology shown, image analysable)

Exclusion criteria

Exclusion criteria: 1. non-paediatric population (as described above).

Design outcomes

Primary

MeasureTime frame
1. Determination of algorithm- and pathology-specific ROC curves, quantification of diagnostic accuracy by means of AUC in the sense of external validation. 2. If no ROC analyses are possible (e.g. if no pathology-specific scores can be issued and only a binary yes/no classification takes place), the evaluation is carried out using standard metrics such as sensitivity / specificity / accuracy etc. 3. Comparison of the diagnostic accuracy of the algorithms used with the sensitivity / specificity achieved by diagnosticians.

Secondary

MeasureTime frame
1. Calculation of inter-/intrareader reliability and correlation metrics between individual readers/reader groups in reading studies (e.g. radiologists vs. paediatric surgeons/paediatricians). 2. Surgical point optimisation on ROC curves (e.g. using the Youden J index).

Countries

Germany

Contacts

Public ContactJan Rudolph

Klinik und Poliklinik für Radiologie, LMU Klinikum

Jan.Rudolph@med.uni-muenchen.de+49 89 4400 73283

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026