Ovarian cancer C56
Conditions
Interventions
Group 1: Over a period of 5 months (April 2024 to September 2024), stool and blood samples from patients undergoing exploratory laparotomy for ovarian cancer after preoperative standard of care will b
Sponsors
Universitätsklinikum Heidelberg, Klinik für Frauenheilkunde
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Ovarian carcinoma, exploratory laparotomy, consent to study
Exclusion criteria
Exclusion criteria: none
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in the gastrointestinal microbiome compared between the groups using stool samples (analysis of 16S rRNA via next generation sequencing (NGS)) preoperatively, on day 3-5 after surgery and after 3 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Effects on patient outcome (parameters: occurrence and severity of postoperative complications (evaluation of clinical data, severity classification using the Clavien/Dindo classification), length of ICU stay, length of hospital stay) - Effects on the immune system (leukocyte populations: analysis via flow cytometry preoperatively, as well as postoperatively on day 1, day 3-5 (depending on stool sample collection date) and after 3 months) | — |
Countries
Germany
Contacts
Public ContactChiara Middel
Universitätsklinikum Heidelberg, Klinik für Anästhesiologie
Outcome results
None listed