Solid tumours of the oesophagus, stomach, duodenum or colon or rectum
Conditions
Interventions
Group 1: Intervention group receives multimodal therapy with whole-body electromyostimulation and exercise therapy (at least once and optionally twice a week, lasting 11-20 minutes, over 12 weeks, 12-
Sponsors
Dreifaltigkeits-Krankenhaus Wesseling
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Patients with oesophageal, gastric, duodenal, colon or rectal cancer following surgery without further therapy and with neoadjuvant and adjuvant therapy - medical clearance for exercise training - written declaration of consent from the study participant
Exclusion criteria
Exclusion criteria: - Participation in another study on the topic of exercise or nutrition - Electronic implants such as pacemakers, pumps, and coronary stents - Cardiac arrhythmia - Implants in the area of application (e.g. breast implants) - Pregnancy - Epilepsy - Wounds and open skin diseases in the area of application of the electrodes - Unhealed operations or bone fractures - Acute inflammatory diseases (e.g. inflammation of the intervertebral discs, bones, vessels, or soft tissue) - Directly after herniated discs or other instabilities such as large abdominal wall hernias - Blood clots (thromboses) - Bone diseases with high-grade osteoporosis - Increased risk of haemorrhage - Fever and illnesses that can be aggravated by physical exertion - Untreated high blood pressure - Blindness - Continuous parenteral nutrition - Metal and electronic parts in the body (e.g. prostheses, metal vascular clips, hearing aids/inner ear/cochlear implants, magnetic dental prostheses, pacemakers, contraceptives)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Muscle mass of the quadriceps muscle (vastus lateralis / rectus femoris) (CSD using ultrasound), T0 baseline & T1 after 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Body composition, using bioimpedance analysis (BIA), T0 baseline & T1 after 12 weeks Performance status, with the help of Karnofsky index, T0 baseline & T1 after 12 weeks Endurance capacity, using spiroergometry, T0 baseline & T1 after 12 weeks Lower limb and upper limb performance, using sit-to-stand test (1 minute) and hand grip strength (dynamometry), T0 baseline & T1 after 12 weeks Fatigue symptoms, using the 13-item FACIT Fatigue Scale, T0 baseline & T1 after 12 weeks Quality of life, using the EORTC QLQ C-30, T0 baseline & T1 after 12 weeks Blood parameters, venous blood sampling (routine examination) as part of oncological aftercare, T0 baseline & T1 after 12 weeks | — |
Countries
Germany
Outcome results
None listed