Characterization of the iridocorneal angle in humans in vivo using OCT gonioscopy.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00033946

Enrollment

200

Registered

2025-09-16

Start date

2024-06-01

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H40.1

Interventions

Group 1: 100 healthy subjects - This group consists of subjects without glaucoma and serves as a control group to study normal conditions of the trabecular meshwork (TM), Schlemm canal (SC) and adjace

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Presence of informed consent, a spherical equivalent < 3 Dpt, and no other ophthalmologic concomitant diseases

Exclusion criteria

Exclusion criteria: Non-consenting adults; persons in closed facilities / in prison

Design outcomes

Primary

Measure	Time frame
Image quality of the OCT volume scans of the TM - evaluation of the clarity and accuracy of the images produced by the OCT devices.	—

Secondary

Measure	Time frame
Ability to visualize the Schlemm's canal (SC) and detect any narrowing in glaucoma - Evaluate the effectiveness of OCT technology in visualizing the SC and identifying changes associated with glaucoma. Comparison of the iridocorneal angle (ICA) between healthy subjects and glaucoma patients - Investigate for differences or specific characteristics that occur in glaucoma patients compared to healthy individuals. Detailed characterization of the TM and SC in vivo - using the knowledge gained from the OCT scans to develop a deeper understanding of the structure and function of these areas of the eye under both normal and pathological conditions.	—

Measure

Time frame

Ability to visualize the Schlemm's canal (SC) and detect any narrowing in glaucoma - Evaluate the effectiveness of OCT technology in visualizing the SC and identifying changes associated with glaucoma. Comparison of the iridocorneal angle (ICA) between healthy subjects and glaucoma patients - Investigate for differences or specific characteristics that occur in glaucoma patients compared to healthy individuals. Detailed characterization of the TM and SC in vivo - using the knowledge gained from the OCT scans to develop a deeper understanding of the structure and function of these areas of the eye under both normal and pathological conditions.

—

Countries

Germany

Contacts

Public ContactThomas Ach

Universitätsklinikum Bonn

thomas.ach@ukbonn.de+491703750772

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026