E78
Conditions
Interventions
Group 1: 8.4 g powdered oyster mushroom per day in the form of a flavored drink powder for four weeks
Group 2: mushroom-free flavored drink powder (control) for four weeks
Sponsors
Universität Bonn
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Moderately elevated LDL cholesterol level: 116 - 190 mg/dL, non-smoker for at least 3 months, written informed consent
Exclusion criteria
Exclusion criteria: Allergies or intolerances against mushrooms or any other food ingredients used in the study, diseases of the liver, gall bladder and/or diabetes and other diseases that may influence the target parameters, pacemaker, intake of lipid-lowering drugs and other medications that may have an influence on the target parameters, (planned) pregnancy, lactation, planned changes in lifestyle, regular intake of supplements that contain ß-glucans or soluble fibers, vegan diet, regular intake of phytosterol-enriched margarine, drug abuse, limited legal capability, participating in another clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Analysis of LDL cholesterol levels (fasting state) before and after intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Analysis of other markers of lipid status, sterol metabolism and of the adaptive immune system (fasting state) before and after intervention | — |
Countries
Germany
Contacts
Public ContactSabine Ellinger
Universität Bonn
Outcome results
None listed