I60 I61 I63 I64
Conditions
Interventions
Group 1: TMS examination during condition 1:
Viewing the mirror image of the right hand (healthy person) or the unaffected hand (patient) while this hand performs a forceps grip with 10% of the maxim
Sponsors
Lurija Institut Kliniken Schmieder Allensbach
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: I. Healthy subjects: 1. Ability to give informed consent to participate in the study 2. Age > 18 years 3. No history of neurological or psychiatric illness 4. Not taking any medication known to affect the excitability of the brain (e.g. benzodiazepines) II. Patients 1. Ability to give consent to participate in the study 2. Age > 18 years 3. Sufficient understanding of the task 4. No or minor pain in the affected arm, measured by visual analog scale 5. First stroke (ischemia or hemorrhage), not longer than 6 months ago 6. Rehabilitation phase C or D 7. Paresis of the upper limb with a strength level of 3 to 4+ or impairment of fine motor skills
Exclusion criteria
Exclusion criteria: I. Healthy subjects: 1. Participants with electronic implants (e.g. pacemakers) 2. Epilepsy 3. Pregnancy 4. Intracranial metal particles (e.g. vascular clips) II. Patients 1. Cognitive impairments that do not allow information about the study (e.g. Wernicke's aphasia, global aphasia, dementia) 2. Participants with poor compliance 3. Pain 4. Participants with electronic implants (e.g. pacemakers) 5. Epilepsy 6. Pregnancy 7. Intracranial metal particles (e.g. vascular clips)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TMS parameters (derivation from the interosseus dorsalis I muscle; stimulation with the butterfly coil): Single stimulus amplitudes, short- and long-latency intracortical inhibition, intracortical facilitation. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Mental chronometry with the box and block test (comparison of motor execution and motor imagery). 2. Vividness of movement imagery questionnaire (German version). 3. Examination of somatosensory functions (vibration sensation, proprioceptive test), as severely impaired sensitivity has a negative impact on the ability to perform mental chronometry and could therefore also have an influence on mirror perception. 4 Edinburgh Handedness Inventory. | — |
Countries
Germany
Contacts
Public ContactJana Stürner
Lurija Institut, Kliniken Schmieder Allensbach
Outcome results
None listed