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Circulating Hsp70 Levels and the Immunophenotype of Peripheral Blood Lymphocytes as Potential Biomarkers for patients with HNSCC

Circulating Hsp70 Levels and the Immunophenotype of Peripheral Blood Lymphocytes as Potential Biomarkers for patients with HNSCC

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00033819
Enrollment
650
Registered
2024-03-06
Start date
2024-03-25
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C76.0 K12.28

Interventions

Group 1: Determination of circulating Hsp70, SCCA, CEA, CTCs and immunophenotyping of lymphocytes in patients with head and neck tumors at t0 (preoperative), t1 (7 days postoperative), t2 (3 months po

Sponsors

Klinikum rechts der Isar, Klinik und Poliklinik für Mund-, Kiefer und Gesichtschirurgie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: All patients with primary squamous cell carcinoma or other tumor entities and abscesses who underwent surgery/therapy in the Department of Oral and Maxillofacial Surgery at the Technical University of Munich as well as healthy volunteers who signed the informed consent to study participation.

Exclusion criteria

Exclusion criteria: - Patients without tumor disease or abscesses - Patients with external tumor aftercare

Design outcomes

Primary

MeasureTime frame
Determination of potential biomarkers: Determination of circulating Hsp70, SCCA, CEA, CTCs and immunophenotyping of lymphocytes in patients with head and neck cancer, in patients with abscesses and in healthy individuals until February 2027

Secondary

MeasureTime frame
Recording of general patient data and forms of therapy

Countries

Germany

Contacts

Public ContactMinli Niu

Klinikum rechts der Isar, Klinik und Poliklinik für Mund-, Kiefer und Gesichtschirurgie

minli.niu@tum.de+49 89 4140 5354

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026