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Effect of unilateral conductive hearing loss and its therapy on neuronal activity of the auditory sys-tem – a PET, MRI/DMI, fNIRS and microphenomenologic study

Effect of unilateral conductive hearing loss and its therapy on neuronal activity of the auditory sys-tem – a PET, MRI/DMI, fNIRS and microphenomenologic study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00033812
Enrollment
160
Registered
2024-03-05
Start date
2024-05-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H90.1

Interventions

Group 1: Study group 1: Patients with unilateral conductive hearing loss that recieved a bone-conductive device or an active middle ear implant Group 2: Study group 2: Patients with unilateral conduc

Sponsors

Uniklinik Freiburg
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Study group 1: - Diagnosis with unilateral conductive hearing loss - Treatment with a bone-conductive device or an active middle ear implant Study group 2: - Diagnosis with unilateral conductive hearing loss - No treatment with a bone-conductive device or an active middle ear implant Study group 1 and 2: - age = 18 years - right handed - German at at least B1 level

Exclusion criteria

Exclusion criteria: - Relevant neurological or psychiatric illness - Circumstances and illnesses that suggest insufficient compliance with the PET or fMRI examination - Pregnancy, breastfeeding - Poorly controlled diabetes mellitus - Study-related radiation exposure from previous study participation - Relevant ophthalmological diseases - Participants do not agree to the communication of incidental findings.

Design outcomes

Primary

MeasureTime frame
Study groups 1 und 2: Neuronal activity of the auditory cortex during acoustic, visual and vibrotactil stimulation (fNRIS, functional near-infrared spectroscopy)

Secondary

MeasureTime frame
Study group 1 - Glucose uptake in the primary auditory coretx and inferior colliculus - interhemispheric connectivity of the primary auditory coretx

Countries

Germany

Contacts

Public ContactIva Speck

Uniklinik Freiburg

iva.speck@uniklinik-freiburg.de+4976127042010

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026