Influence of an oral health-optimized diet on the treatment success of non-surgical periodontal therapy. A randomized controlled trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00033784

Enrollment

Registered

2024-03-07

Start date

2024-04-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K05.3 K05

Interventions

Group 1: Patients with periodontitis (stage II-IV, grade B and C, generalized) receive nutritional therapy (mainly plant-based wholefoods) in addition to non-surgical periodontal therapy, which is tau

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Patients with stage II-IV periodontitis, grade B and C, generalized - Presence of at least 14 teeth - Diet according to a "western diet" (high proportion of processed simple carbohydrates, saturated fatty acids, low in micronutrients; determined by RKI-DEGS questionnaire) - Signed consent to participate - Consent to change the diet as far as possible or, in the case of control group allocation, to maintain it for the study period

Exclusion criteria

Exclusion criteria: - Patients with periodontitis who, according to the guidelines, have an indication for adjuvant antibiotic therapy (periodontitis stage III-IV grade C in patients 20 cigarettes/d). The proportion of smokers in the study should not exceed 1/3 of the number of participants. - Pregnancy and lactation - Serious or infectious general diseases (e.g. tumor diseases, HIV in the AIDS stage) - Diseases that do not allow the dietary protocol (e.g. glycogen storage disease, food intolerances) - Unadjusted diabetes mellitus and other diseases of the carbohydrate or fat metabolism

Design outcomes

Primary

Measure	Time frame
The periodontal probing depths are recorded at baseline, after 3 months and after 6 months. The primary endpoint is the reduction in probing depths after 6 months of treatment compared to the baseline.	—

Secondary

Measure	Time frame
At baseline, after 3 months and after 6 months, gingival inflammation (according to gingival index (GI)), plaque index (PI), clinical attachment level, bleeding on probing (BOP), need for re-instrumentation, as well as weight, BMI and blood pressure are recorded. The changes in these parameters from baseline compared to 6 months are considered as secondary endpoints.	—

Countries

Germany

Contacts

Public ContactJohan Wölber

Klinik für Zahnerhaltungskunde & Parodontologie, Universitätsklinikum Freiburg

johan.woelber@uniklinik-freiburg.de0761270473100

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026