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Using visual mapping to study the effects of schizophrenia Resilience genes

Using visual mapping to study the effects of schizophrenia Resilience genes - SAPPHIRE

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00033731
Enrollment
154
Registered
2025-03-05
Start date
2026-09-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy participants

Interventions

Group 1: The goal of the current imaging genetics fMRI study is to develop a novel visual mapping paradigm combining the estimation of population receptive field (pRF) sizes with the functional deline

Sponsors

Forschungsdekanat - Fachbereich Medizin - Goethe Universität Frankfurt
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Healthy participants; age 18-60 years; who can be scanned in an MRI

Exclusion criteria

Exclusion criteria: - neurological illness (past or present) including traumatic brain injury - history of neuropsychiatric conditions according to DSM-V criteria - family history for major mental disorder according to DSM-V criteria - current psychotropic pharmacological treatment - current medication other than psychotropic pharmacological treatment - regular use of recreational drugs including tobacco and nicotine - standard exclusion criteria for magnetic resonance imaging (metal objects in the body or tattoos with metal-containing colour) - colorblindness or red-green-colorblindness

Design outcomes

Primary

MeasureTime frame
Correlation of receptive field size with PRS-resilience for schizophrenia

Secondary

MeasureTime frame
Correlation of higher-order visual areas with PRS-Resilience for schizophrenia

Countries

Germany

Contacts

Public ContactMishal Qubad

Klinik für Psychiatrie, Psychosomatik und Psychotherapie, Universitätsklinikum Frankfurt, Goethe Universität

mishal.qubad@med.uni-frankfurt.de+4969630186504

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026