Transcranial electrical stimulation to prevent the occurrence of postoperative delirium

Transcranial electrical stimulation to prevent the occurrence of postoperative delirium - MoDeSt

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00033703

Enrollment

225

Registered

2024-02-23

Start date

2024-02-05

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F05.8 R52.0 R52.2

Interventions

Group 1: post-operative transcranial direct current stimulation Group 2: post-operative transcranial alternating current stimulation Group 3: post-operative sham stimulation

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: - Elective surgical operation or procedure with a planned duration of more than 60 minutes - Able to give informed consent independently - Exsistence of a signed informed consent form

Exclusion criteria

Exclusion criteria: - Known neurological or psychiatric illness, in particular epilepsy or a history of epileptic seizures - Contraindications for tDCS/tACS application - Long-term medication with CNS-active drugs - Isolation due to multi-resistant pathogens - Inability of the patient to read or speak German

Design outcomes

Primary

Measure	Time frame
Incidence of post-operative delirium	—

Secondary

Measure	Time frame
1. the severity, duration and phenotype of post-operative delirium 2. post-operative pain 3. EEG markers 4. biomarkers of clinical routine 5. inflammatory delirium-associated biomarkers	—

Countries

Germany

Contacts

Public ContactViktor Bublitz

Klinik für Anästhesie, Intensiv-, Notfall- und Schmerzmedizin

viktorkarl.bublitz@med.uni-greifswald.de+4938348622262

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 20, 2026