Impact of a low glycemic load diet on oncological course after surgical resection of colorectal liver metastases.

Impact of a low glycemic load diet on oncological course after surgical resection of colorectal liver metastases. - CALIMET

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00033678

Enrollment

Registered

2024-06-21

Start date

2018-03-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C78.7

Interventions

Group 1: Intervention group: After surgical resection of colorectal liver metastases, the diet is changed to a low glycemic load. Group 2: Control group: The usual diet is continued after surgical res

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Metachronous colorectal liver metastases. Fong score >= 4 Written informed consent to participate in the study.

Exclusion criteria

Exclusion criteria: - Type 1 diabetes mellitus - Chronic renal failure (GFR <= 60 ml/min) - Any factor that may limit the patient's ability to cooperate during the study (e.g., mental function or substance abuse) - Significant cognitive impairment, clinically relevant or progressive disease (e.g., liver, kidney, cardiovascular, respiratory, vascular, brain, metabolic, thyroid) that could affect the course of the study. - Concurrent participation in another AMG/MPG study - Existing dependence on alcohol, medication, drugs or nicotine abuse during the fasting period - Insufficient mental capacity to cooperate - Eating disorders - Kidney stones - Fatty acid oxidation disorders - Ketolysis/ketoneogenesis defects - Gluconeogenesis defects - Hyperinsulinism (e.g. nesidioblastoma) - Pyruvate carboxylase deficiency - Known bleeding tendency or use of anticoagulant medication (PTT, INR and platelets will be checked prior to study entry) - Pregnancy and lactation - Suspected noncompliance - Special diet for medical reasons

Design outcomes

Primary

Measure	Time frame
Determination of the influence of a diet with a low glycemic load on the oncological course after surgical resection of colorectal liver metastases. For this over a period of 12 months, clinical imaging data are recorded at a total of 4 visits.	—

Secondary

Measure	Time frame
Determination of the patient compliance with the change in diet.	—

Countries

Germany

Contacts

Public ContactThorsten Cramer

Uniklinik RWTH Aachen Allg.-, Viszeral-, Kinder & Transplantationschirurgie

tcramer@ukaachen.de+492418036353

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026