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Detection of abdominal surgical complications through the application of machine learning algorithms and natural language processing models - a retrospective, multicentric, diagnostic accuracy study

Detection of abdominal surgical complications through the application of machine learning algorithms and natural language processing models - a retrospective, multicentric, diagnostic accuracy study - CASSANDRA retro

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00033658
Enrollment
10000
Registered
2024-02-19
Start date
2022-01-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

German OPS-2024 Code

Interventions

Group 1: All patients who underwent a major visceral surgical operation of the upper and lower gastrointestinal tract, as well as the hepatobiliary system, between 2015 and 2022 at one of the two surg

Sponsors

Chirurgische Klinik Campus Mitte | Campus Virchow Klinikum, Charité - Universitätsmedizin Berlin
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Major visceral surgical resections on the organ systems of the liver, pancreas, stomach/esophagus, and intestines according to the following OPS (Operation and Procedure Keys) groups: ? 5-454.0 to 5-545.y ? 5-465.0 to 5-465.y ? 5-466.0 to 5-466.y ? 5-455.0 to 5-455.y ? 5-456.0 to 5-456.y ? 5-484.0 to 5-484.y ? 5-485.0 to 5-485.y ? 5-423.0 to 5-423.y ? 5-424.0 to 5-424.y ? 5-425.0 to 5-425.y ? 5-426.0 to 5-426.y ? 5-434.0 to 5-434.y ? 5-435.0 to 5-435.y ? 5-436.0 to 5-436.y ? 5-437.0 to 5-437.y ? 5-438.0 to 5-438.y ? 5-524.0 to 5-524.y ? 5-525.0 to 5-525.y ? 5-502.0 to 5-502.y ? 5-501.0 to 5-501.y

Exclusion criteria

Exclusion criteria: Age < 18 years

Design outcomes

Primary

MeasureTime frame
Intensive care unit-required sepsis episode occurring during hospital stay until discharge. This is defined by: 1. Transfer/treatment in an intensive care unit. 2. A change in the Sequential Organ Failure Assessment (SOFA) score by 2 points. 3. Reoperation, radiological, or endoscopic intervention.

Secondary

MeasureTime frame
Occurrence of additional major complications (e.g., bleeding events, cardiopulmonary complications, acute kidney failure) during the inpatient treatment course, defined according to the respective international standards, as well as the 90-day follow-up.

Countries

Germany

Contacts

Public ContactMax Magnus Maurer

Chirurgische Klinik Campus Mitte | Campus Virchow Klinikum, Charité - Universitätsmedizin Berlin

max-magnus.maurer@charite.de+49 30 450652418

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026