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Investigating the reliability and validity of clinical and instrumental assessments of xerosis cutis in the context of vulnerable stages of life: a descriptive study

Investigating the reliability and validity of clinical and instrumental assessments of xerosis cutis in the context of vulnerable stages of life: a descriptive study - CRC-SP-A-44

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00033630
Enrollment
40
Registered
2024-06-04
Start date
2024-06-07
Completion date
Unknown
Last updated
2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

L85.3

Interventions

Group 1: 40 people aged 40 - 85 years with a tendency to dry skin (possibly visible scaling on arms and legs). After the participants have given their informed consent and the inclusion and exclusion

Sponsors

Charité Universitätsmedizin Berlin, Abteilung für Dermatologie, Venerologie und Allergologie, Clinical Research Center for Hair and Skin Science and the Institute of Clinical Nursing Science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 85 Years

Inclusion criteria

Inclusion criteria: o Predisposition to dry skin o At least 50% of participants must exhibit clinically visible scaling on arms and legs o Written, informal consent, provided in person (the participant must be able to communicate) o Willingness and ability to fulfill the requirements of the study Vulnerable phases refer to the following circumstances: Progressive frailty (from the age of 70) requires considerable psychological adjustments. This phase is characterized by increasing physical weakness and an increased risk of falls and injuries. With age, chronic illnesses such as osteoporosis and cardiovascular disease become more frequent, affecting physical fitness and mobility. Women aged around 40 in particular go through hormonal changes due to the menopause, which bring hot flushes, mood swings and other symptoms. These changes mark the end of the reproductive years and require adjustments to the new physical and emotional realities.

Exclusion criteria

Exclusion criteria: o Participants diagnosed with active atopic dermatitis or other inflammatory chronic skin conditions / severe dermatological disorders at the discretion of the investigator o Subjects, who are unable to understand the subject’s information, e.g. for linguistic or psychiatric reasons, and to give their consent o Subjects, who have forfeited their freedom by administrative or legal decision or under guardianship o Subjects currently participating in or in the exclusion period of another study

Design outcomes

Primary

MeasureTime frame
The study is based on an exploratory descriptive design and no primary endpoints are defined.

Secondary

MeasureTime frame
The study is based on an exploratory descriptive design and no secondary endpoints are defined.

Countries

Germany

Contacts

Public ContactKathrin Hillmann

Charité Universitätsmedizin Berlin, Abteilung für Dermatologie, Venerologie und Allergologie, Clinical Research Center for Hair and Skin Science

kathrin.hillmann@charite.de(0)30 450 518 499

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026