G72.80
Conditions
Interventions
Group 1: Sham-Control-Group (BFR-Application with 20mmHg)
Group 2: Blood-Flow-Restriction + Electromyostimulation Group (BFR-Application with 100% of the individual limb occlusion pressure)
Group 3: E
Sponsors
Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: The study includes all patients under intensive care monitoring and therapy with a length of stay >48 hours in the surgical intensive care units of the UKB All participating patients have signed the patient consent form for participation in the study and the privacy policy after extensive explanation, clarification and information or were represented by the authorized spouse as part of the spousal proxy after extensive explanation
Exclusion criteria
Exclusion criteria: Acute or chronic infections of the extremities Open wounds on the lower extremity Pregnancy and breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Muscle mass: Measured by thigh circumference, ultrasound Muscle function: Measured by surface electromyography, hand grip strength Time of Measurement: Pre-Intervention phase, Post-Intervention phase, Discharge from ICU, Discharge from the Hospital | — |
Secondary
| Measure | Time frame |
|---|---|
| Hospital or 28d mortality ICU length of stay, hospital length of stay Health-related quality of life (SF-36, WHODAS 2.0 on the day of discharge, 6 and 12 months after discharge) Return to work rate, job level compared to previous status, GdB | — |
Countries
Germany
Contacts
Public ContactStefan Ehrentraut
Klinik für Anästhesiologie und Operative Intensivmedizin
Outcome results
None listed