Impacts of Epigenetics and psycho-social stress on male infertility: new pathways in fertility management?

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00033587

Enrollment

150

Registered

2024-08-12

Start date

2025-02-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

N46

Interventions

Group 1: Healthy and fertile males with normal sperm parameters (consultation visitors for fertility diagnostics): i. sperm and blood sample during out-patient consultation for fertility diagnostics (

Eligibility

Sex/Gender

Male

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Written consent

Exclusion criteria

Exclusion criteria: <18 years of age, denial of consent, cognitive disorder

Design outcomes

Primary

Measure	Time frame
Primary outcomes: epigenetics profiles in semen and blood (especially DNA-methylation), cortisol levels in blood and semen, scores in questionnaires on psycho-social stress.	—

Secondary

Measure	Time frame
Age, lifestyle (especially smoking and alcohol usage), body mass index	—

Countries

Germany

Contacts

Public ContactMax Träger

Klinik für Urologie, Universitätsklinikum Freiburg

max.michael.traeger@uniklinik-freiburg.de004976127028930

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026